Synaptic transmission

  • describe and explain the transmission of an action potential in a myelinated neurone and its initiation from a resting potential (the importance of sodium and potassium ions in impulse transmission should be emphasised)
  • describe the structure of a cholinergic synapse and explain how it functions, including the role of calcium ions
  • outline the roles of synapses in the nervous system in allowing transmission in one direction and in allowing connections between one neurone and many others (summation, facilitation and inhibitory synapses are not required)
  • describe the roles of neuromuscular junctions, transverse system tubules and sarcoplasmic reticulum in stimulating contraction in striated muscle